Synthesis and Analysis of 1-Boc-4-Piperidone

The preparation of 1-Boc-4-piperidone is a common reaction in organic chemistry. This molecule serves as a valuable building block for the construction of more complex molecules, particularly in pharmaceutical and agrochemical research. The procedure typically involves the protection of the nitrogen atom in 4-piperidone with a tert-butoxycarbonyl (Boc) group. This modification enhances its reactivity towards further functionalization. The resulting 1-Boc-4-piperidone can be completely characterized using a variety of techniques, including nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS), and infrared (IR) spectroscopy. These methods allow for the confirmation of its structure and concentration.

Pharmacological Potential of 1-Boc-4-Piperidone

1-Boc-4-piperidone, a synthetically accessible derivative of piperidine, has garnered increasing attention within the scientific community due to its promising pharmacological potential. This versatile compound exhibits a wide range of biological activities, including anti-inflammatory, analgesic, and neuroprotective effects. Researchers are actively investigating its utilization in various therapeutic areas, including the treatment of autoimmune disorders. Furthermore, 1-Boc-4-piperidone's structural flexibility allows for alteration to optimize its pharmacological properties and target specific disease pathways.

• Animal model research have demonstrated the effectiveness of 1-Boc-4-piperidone in a variety of models, suggesting its potential as a valuable therapeutic agent.
• Clinical trials are currently underway to further evaluate the safety and efficacy of 1-Boc-4-piperidone in human patients.

Structure-Activity Studies on 1-Boc-4-Piperidone Derivatives

Investigation of SARs in 1-Boc-4-piperidone derivatives is a essential endeavor for the design of novel therapeutic agents. These studies involve the impact of structural modifications on the pharmacological potency of these compounds. Investigators typically utilize a variety of methods to determine the correlation between structure and activity. This insight can inform the design of more potent and targeted therapeutic agents.

• Alterations to the piperidone ring are often investigated for their effect on efficacy.
• Functional groups attached to the scaffold can significantly impact the pharmacological activity of the compounds.
• Structure-activity relationship studies provide valuable insights for the enhancement of therapeutic agents based on 1-Boc-4-piperidone derivatives.

Computational Modeling of Affinity Interactions

To elucidate the intricate binding interactions between 1-Boc-4-Piperidone and its target proteins, computational modeling methods are employed. Molecular docking simulations provide insights into the energetically favorable binding poses, revealing key residues involved in the interaction network. Structural analysis allows for the identification of essential pharmacophoric features contributing to the Specificity of 1-Boc-4-Piperidone. Furthermore, molecular dynamics simulations explore the dynamic nature of the binding complex over time, shedding light on potential conformational changes and ligand mobility. These computational approaches contribute significantly to a comprehensive understanding of the molecular underpinnings of 1-Boc-4-Piperidone's biological activity.

Development of Novel Therapeutics Utilizing 1-Boc-4-Piperidone

The development of novel therapeutics utilizing 1-Boc-4-piperidone presents a significant avenue for addressing various therapeutic challenges. 1-Boc-4-piperidone, attributed to its adaptability, serves as a valuable building scaffold for the design of novel drug candidates. This cyclic compound can be readily tailored to synthesize a diverse array of derivatives possessing unique pharmacological properties.

Scientists in the area are actively exploring the potential employment of 1-Boc-4-piperidone in the development of therapeutics for conditions such as inflammatory disorders. The configuration of 1-Boc-4-piperidone enables for incorporation of various pharmacophores that engage with specific targets involved in disease pathways.

Laboratory studies suggest that 1-Boc-4-piperidone derivatives display favorable antimicrobial activity. This growing Synonyms:79099-07-3;1-Boc-4-piperidone;N-Boc-4-piperidone;tert-Butyl 4-Oxopiperidine-1-carboxylate;n-(tert-butoxycarbonyl)-4-piperidone;1-Boc-4-piperidinone;n-tert-butoxycarbonyl-4-piperidone;1-t-boc-4-piperidone;1-boc-piperidin-4-one;MFCD00151800;Boc-4-piperidone;1-(tert-Butoxycarbonyl)-4-piperidone;4-oxo-piperidine-1-carboxylic acid tert-butyl ester;n-boc-4-piperidinone;1-n-boc-4-piperidone;N-BOC-piperidin-4-one;N-tert Boc-4-piperidone;1-PIPERIDINECARBOXYLIC ACID, 4-OXO-, 1,1-DIMETHYLETHYL ESTER;tert-Butyl 4-oxo-1-piperidinecarboxylate;N-BOC-PIPERIDINE-4-ONE;1-tert-butoxycarbonyl-4-piperidone;1-tert-Butoxycarbonylpiperidin-4-one;4-Oxo-1-piperidinecarboxylic Acid tert-Butyl Ester;Boc-4-piperidon;1-Boc4-piperidone;tert-butyl 4-oxopiperidinecarboxylate;Boc-piperidin-4-one;N-BOC 4-piperidone;n-boc-piperid-4-one;n-t-boc-4-piperidone;N-Boc-4-oxopiperidine;N-boc piperidin-4-one;1-Boc piperdin-4-one;tert-butyl 4-oxo-piperidine-1-carboxylate;1-Boc piperidin-4-one;N-Boc-4-oxo-piperidine;Maybridge1_004217;N-tert-Boc 4-piperidinone;SCHEMBL31028;t-butoxycarbonyl-4-piperidone;1-Boc-4-piperidone, 98%;N-t-butoxycarbonyl4-piperidone;1-t-butoxycarbonyl 4-piperidone;1-t-butoxycarbonylpiperid-4-one;N-t-Butoxycarbonyl-4-piperidone;tert-butoxycarbonyl-4-piperidone;1-t-Butoxycarbonyl-4-piperidone;HMS553H17;1-tertbutoxycarbonyl-4-piperidone;4-oxopiperidine, n-boc protected;DTXSID60352875;N-(t-butoxycarbonyl)4-piperidone;N-tert-butoxycarbonyl-4piperidone;N-tert-butoxycarbonyl4-piperidone;1-t-butoxycarbonyl-4-piperidinone;1-t-butoxycarbonylpiperidin-4-one;1-t-butoxycarbonylpyperidin-4-one;1-t-butyloxycarbonyl-4-piperidone;N-t-butoxycarbonylpiperidin-4-one;N-t-butyloxycarbonyl-4-piperidone;1-(t-butoxycarbonyl)-4-piperidone;1-t-butoxycarbonyl-4-oxopiperidine;1-tert-Butoxycarbonylpiperid-4-one;N-(t-butoxycarbonyl)-4-piperidone;N-t-butoxycarbonyl piperidin-4-one;1-t-butoxycarbonyl-piperidin-4 one;1-t-butyloxycarbonyl-4-piperidinone;1-t-butyloxycarbonylpiperidin-4-one;BCP27224;CS-B0410;N-t-butyloxycarbonyl-4-piperidinone;N-tert-Butoxylcarbonyl-4-piperidone;1-(t-butyoxycarbonyl)-4-piperidone;1-t-butoxycarbonyl piperidine-4-one;N-tert-butoxycarbonyl -4-piperidone;N-tert-butoxycarbonyl-4-piperidinone;N-tert-butoxycarbonylpiperidin-4-one;N-tert-butyloxycarbonylpiperid-4-one;1(tert-Butoxycarbonyl)-4-piperidone;1-(t-butyloxycarbonyl)-4-piperidone;1-tert-butoxycarbonyl-4-piperidinone;1-tert-Butyloxycarbonyl-4-piperidone;AC-762;BBL028282;N-tert-Butyloxycarbonyl-4-piperidone;STL195481;tert-butyloxycarbonyl-4-oxopiperidine;1-(t-butoxycarbonyl)-4-oxopiperidine;1-tert-butoxycarbonyl-4-oxopiperidine;N-tert-butoxycarbonyl-piperidin-4-one;t-butyl 4-oxopiperidin-1-carboxylate;1-(tert-butyoxycarbonyl)-4-piperidone;1-tert-butoxycarbonyl-4-ketopiperidine;1-tert-butoxycarbonyl-piperidin-4-one;1-tert-butyloxycarbonyl-4-piperidinone;1-tert-butyloxycarbonylpiperidin-4-one;AKOS005146164;N-tert-butyloxycarbonylpiperidin-4-one;t-butyl 4-oxo-1-piperidinecarboxylate;t-butyl 4-oxopiperidine-1-carboxylate;t-butyl-4-oxo-1-piperidinecarboxylate;t-butyl-4-oxopiperidine-1-carboxylate;1-(t-butoxycarbonyl)-4-oxo-piperidine;1-(tert-butoxycarbonyl) -4-piperidone;1-tert-butoxycarbonyl piperidine-4-one;1P-563S;PB33823;1-(tert-butoxycarbonyl)-4-piperidinone;1-(tert-butoxycarbonyl)piperidin-4-one;1-(tert-butyloxycarbonyl)-4-piperidone;t-butyl 4-oxo-1-piperidine carboxylate;t-Butyl 4-oxo-1-piperidine-carboxylate;t-butyl-4-oxo-1-piperidine carboxylate;t-butyl-4-oxo-piperidine-1-carboxylate;tert-butyl 4-oxo-1-piperidmecarboxylate;tert-butyl 4-oxopiperidin-1-carboxylate;tert-butyl-4oxo-1-piperidinecarboxylate;1-(tert-butyl oxycarbonyl)-4-piperidone;N-(tert-butoxycarbonyl)-piperidin-4-one;tert-butyl 4-oxopiperidine-l-carboxylate;Tert-butyl-4-oxo-1-piperidinecarboxylate;tert-butyl-4-oxopiperidine-1-carboxylate;1-(tert-butyloxycarbonyl)-4-piperidinone;1-(tert-butyloxycarbonyl)piperidin-4-one;BP-12383;SY001953;tert-butyl piperidin-4-one-1-carboxylate;tert.butyl 4-oxo-piperidin-1-carboxylate;1-(Tert-butyloxycarbonyl)piperidine-4-one;tert-butyl 4-oxo-1-piperidine carboxylate;tert-butyl 4-oxo-1-piperidine-carboxylate;tert-butyl-4-oxo-1-piperidine carboxylate;tert. butyl 4-oxo-piperidin-1-carboxylate;tert.butyl 4-oxo-piperidine-1-carboxylate;1-tert-butyl 4-oxo-1-piperidinecarboxylate;tert. butyl 4-oxo-piperidine-1-carboxylate;A9892;AM20100788;B2365;BB 0269517;FT-0600023;FT-0651555;1-(1,1-dimethylethoxycarbonyl)-4-piperidone;EN300-43845;N-(1,1-di-methylethoxycarbonyl)-4-piperidone;1-(1,1-dimethylethoxycarbonyl)-4-piperidinone;1,1-dimethylethyl 4-oxopiperidine-1-carboxylate;1-(TERT-BUTOXYCARBONYL)-4-OXOPIPERIDINE;4-oxopiperidine-1-carboxylic acid t-butyl ester;1,1-dimethylethyl 4-oxo-1-piperidine carboxylate;4-oxo-piperidine-1-carboxylic acid tert-butylester;4-oxopiperidine-1-carboxylic acid tert-butyl ester;t-butyl 4-oxotetrahydropyridine-1(2H)-carboxylate;1-Boc-4-piperidone, puriss., >=99.0% (HPLC);4-Oxo-piperidin-1-carboxylic acid tert-butyl ester;4-oxo-piperidine-1 carboxylic acid tert-butyl ester;Q-201423;4-oxo-piperidine-1- carboxylic acid tert-butyl ester;1,1-DIMETHYLETHYL 4-OXO-1-PIPERIDINECARBOXYLATE;F0001-2081;Z385474368;4-oxo-1-piperidinecarboxylic acid, 1,1-dimethylethyl ester;4-OXO-1-PIPERIDINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER literature highlights the capability of 1-Boc-4-piperidone as a valuable scaffold for the design of novel therapeutics for.

Synthesis and Application of 1-Boc-4-Piperidone in Organic Chemistry

1-Boc-4-piperidone, a versatile precursor, has emerged as a key compound in organic chemistry. Its unique structural features, including the protected amine group and the readily modifiable carbonyl moiety, render its wide application in the assembly of complex organic molecules.

One prominent application involves the synthesis of bioactive entities, such as pharmaceuticals and agrochemicals. The stability of the Boc protecting group allows for selective modifications at other positions on the piperidine ring, enabling the creation of diverse chemical libraries for drug discovery. Additionally, 1-Boc-4-piperidone serves as a valuable starting material for the synthesis of heterocyclic molecules, which are prevalent in natural products and pharmaceuticals.